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Patient-Derived Xenograft (PDX) mouse model

Basic Information

　　To gain a deeper understanding of the biological characteristics of tumors and the efficacy of drug treatments, a mouse model (PDX) directly derived from human tumor tissue has been established. The xenograft tumor model is established by transplanting fresh human tumor tissue into immunodeficient mice. Since the transplanted tissue originates from a patient's tumor, it maximally preserves the tumor's specificity. Moreover, as the tissue is not artificially cultured, its biological characteristics remain intact and closely resemble clinical conditions. This model is considered the most advanced tumor animal model currently available.
　　Jennio has many years of experience in building PDX models and has established collaborations with multiple top-tier hospitals to build Oncology Precision Therapy Center. Moreover, Jennio has access to a wide range of clinical samples from various departments of hospitals and built a PDX tumor library with more than 300 sample, providing assistance to clients in related oncology research.

Services We Provide

　　①Stable animal model (including but not limited to):
　　PDX model of Pancreatic cancer
　　PDX model of hepatocellular carcinoma
　　PDX model of lung cancer
　　PDX model of gastric carcinoma
　　PDX model of breast cancer
　　PDX model of cervical cancer
　　PDX model of nasopharynx cancer
　　PDX model of bladder cancer
　　PDX model of colorectal cancer
　　②Professional detection system (including but not limited to):
　　Histopathological examination
　　Construction of primary tumor cell lines
　　STR identification.
　　Gene sequencing
　　immumohistochemical staining
　　Evaluation of drug efficacy

Procedure of Services

Features

　　①Jennio has abundant clinical resources and a clinical tumor sample library.
　　②With years of experience in PDX animal model construction, we can provide customers with stable animal models for in vivo drug efficacy research.
　　③Jennio has professional research teams with members having years of GLP preclinical trial experiences, and provides high levels of drug efficacy research based on the standardized professional operations and strict quality control management systems.
　　④Jennio has well-equipped testing platforms that can meet various clinical indicator testing requirements.
　　⑤Jennio has experienced preclinical research experts who have collaborated with several well-known domestic pharmaceutical companies to complete preclinical efficacy testing and drug clinical trial application, providing customers with strong support for drug research and development.

Representative Case

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